Gene Expressions takes another look at Cultural Regions of the United States. One quote:
One of the obvious inferences that can be made from the data is that New Englanders shaped the culture and polities of many regions of the United States where they were a minority. Boston was self-consciously the Athens of America. Not only does this region have many elite universities, but the more prominent state institutions such as the Universities of Michigan and Wisconsin were started in part by Yankees who valued these sorts of public investments. The role of New Englanders in primary education throughout the United States is well known, Puritan America may have been the world's first universally literate society, and they were intent on spreading this trait across every group into the United States.
Though New Englanders were often outnumbered by later waves of immigration from the Upland South (e.g., Scots-Irish), as in the Pacific Northwest's Willamette Valley or Northern California, they were overrepresented among the intelligentsia and captains of industry. In the western Upper Midwest Yankees were absorbed by a sea of Northern European immigration, but for several generations they retained a hold on the cultural and capital classes. One might contend that many of the complaints about the "brainwashing" which occurs at elite universities of bright but impressionable young men and women is simply the latest manifestation of the conflict between numerically superior Middle America and the elitist New England outlook (even outside of New England, see Leland Stanford's biography).