Sometimes my gym boss wants me to do 8-12 reps per powerlift set. I hate that. I like 5 reps/set and 5 working sets. That's 25 tough efforts.
Since powerlifts (more or less including deadlift, barbell squat, military press, bench press, pullups/pull downs, dumbell or barbell row) are the core of any strength-building or strength maintenance program, approaching them right is critical for effectiveness.
Generally speaking, high rep exercises of any sort are more aimed at muscle endurance and maintenance than at strength-building. Of course, we want both, but it's a matter of emphasis and there are plenty of ways to build muscle endurance other than heavy powerlifts.
So for pure strength (bone and muscle), I want to push to my limits and show some improvement each month. So, for each powerlift session, I want to do one warm-up set then 5 sets of 5 reps ramping up in weight to finish at my absolute limit of 5, or just past it (thus needing a spotter just in case). Pushing the envelope.
I understand that my boss sometimes likes to push the powerlift reps with lesser weight, but 5s feel right to me. With 8-12, I just find myself wanting to get it over with. That's not the right attitude.
To use the example of chest strength, if I do bench 5X5 one day, and a few sets of 30 pushups on another day, the former is 100% strength, and the latter 20% strength and 80% endurance. All good for fitness.