The great Okefenokee Swamp - 430,000 acres straddling Georgia and Florida.
Mrs. BD is talking me into doing a kayak trip through it. Being the home of Pogo, I should be more enthused but I watched this excellent video and think I got the gist of it without having to actually do it. Lots of reptiles.
Really, not enough interesting bird life there. Everglades, or the Georgia barrier islands are better for that.