‘Ignorance more frequently begets confidence than does knowledge.’
Charles Darwin, via an Aeon piece on the Dunning-Kruger Effect (how poorly-informed people tend to over-estimate their competence, while the best-informed tend to doubt themselves)
Interestingly, really smart people also fail to accurately self-assess their abilities. As much as D- and F-grade students overestimate their abilities, A-grade students underestimate theirs. In their classic study, Dunning and Kruger found that high-performing students, whose cognitive scores were in the top quartile, underestimated their relative competence.
Moral: Self-doubt is always a rational position, and a good foundation for a realistic self-confidence. Maggie's Farmers tend towards wholesome skepticism about everything, including oneself.