This is a downer for Mardi Gras and Carnival season, the modern Saturnalias where no rules apply and reckless hedonism is in the air, but I'll post it anyway like a fuddy-duddy:
I am not sure how to define "natural" for human beings when humans are the ultimate culture-building and society-building animal. For humans, relationship-building and relationship-maintenance are complex, demanding, and sometimes seem almost impossible. Perhaps "natural," though.
Being an acceptable member of a bourgeois society and culture requires hundreds of external restraints (laws, rules, conventions, and expectations) and self-restraints (mostly against temptations and impulses and for reputation-protection). Bourgeois Westerners do not do many very "natural" things like pooping in the park, clubbing people who piss us off, grabbing genitalia when the impulse hits us, stealing people's purses, shooting a neighbor's dog to roast on the backyard grill.
As in ancient times when aristocrats and overlords lived without the constraints of the common folk and the stolid gentry, the Western world still has subcultures which are "above" - or you could call it "below" - the respectable bourgeois Judeo-Christian norms. I am thinking of the special subcultures of Hollywood, Washington, and the like where celebrity, money, and power can exist with separate rules. I am also thinking of some Fishtown subcultures, Tattooland, where there are different standards and expectations.
I must agree with Scarlett Johanssen that monogamy is not "natural" for humans although there is much variation in how libidinally- or id-driven people are. It is definitely not natural for me if some of my X-rated fantasies are evidence but, by behaving myself in many "unnatural" ways, I have managed to build a solid happy life without harming very many people, without blowing up my life, and without too much burden of guilt.
Bill Clinton and Scarlett Johanssen and all the others are free to live as they choose. Tabloid fodder is necessary to drive eyeballs. Perhaps that is why Miss Scarlett made her honest statement about her libidinal intentions. As some guy said on some site, "So I still have a chance to get it on with Scarlett?" Yes, maybe you do if you act charming and catch her in the right mood. Buy her a cocktail and act soulful and deep, wounded but brave. It might work on her and, despite talent, she is not overly bright. Seduction is natural and women like love and sex.
Women are far better at that game than men, however. Women have the power.