Columbia Psychiatry's Prof. Myron Hofer, MD has had a career-long research interest in developmental psychobiology and psychogenetics. His side interest in psychoanalytic theory has been contributory to that.
A recent paper of his summarizes the field: The emerging synthesis of development and evolution: A new biology for psychoanalysis.
His most recent fascination is with epigenetics and how gene expression is affected by environment and spans generations. Gene expression - not genes - is transmissable. The egg from which we were hatched was formed in our Mom's ovary while she was still gestating inside Grandma's uterus. Thus many influences, all in nature's interest in providing variety for adaptation and natural selection.