People joke about how bitchy and cranky, if not downright hostile, many women become around menopause. Bitchy, cranky, and raging may drive family members and friends away, but are not depression in themselves. On the plus side, sometimes, women become much more horny as their estrogen lowers in proportion to their testosterone (yes, women's bodies do produce some of that).
However, menopause-related clinical depression happens, not uncommonly.
Fortunately, we have ways to quiet these demons nowadays. Hormone replacement, antidepressants, or both.