We are a commune of inquiring, skeptical, politically centrist, capitalist, anglophile, traditionalist New England Yankee humans, humanoids, and animals with many interests beyond and above politics. Each of us has had a high-school education (or GED), but all had ADD so didn't pay attention very well, especially the dogs. Each one of us does "try my best to be just like I am," and none of us enjoys working for others, including for Maggie, from whom we receive neither a nickel nor a dime. Freedom from nags, cranks, government, do-gooders, control-freaks and idiots is all that we ask for.
This is something that gets obscured in today's medical reporting--everyone, as they get older, will get sick for some reason and die at some point. The biggest risk factor for heart disease and cancer isn't BMI, cholesterol, blood pressure, etc....it's age. And to a large extent, the incidence of those diseases is random; doing everything right lowers your risk of disease, but not to zero, and usually not to that small a fraction of the risk for the general population.
The point is not to live forever or reduce risks.
It's to slow aging to extend healthy life. That would provide more time for further slowing.
Because the human body is the most-complex system of systems we know of, it will take time.
The good news is that slowing is already underway.
The bad news is that current adults probably won't live long enough to reap the benefits.
Nick Lane argues that the unifying underlying syndrome is your mitochondria wearing out. If we could find some way to address that, with pristine copies of the original mitochondrial DNA, we'd be taking a stab at all of the age-related infirmities at once, rather than trying to treat all the symptoms piecemeal.